The UAMS Department of Anesthesiology has both investigator-initiated and industry sponsored projects. These are divided between basic and clinical research activities, and are funded by the department, industry and the NIH.

Numerous opportunities exist for research participation. Residents can participate in the development of case reports/series, industry-sponsored drug and device studies, and NIH-funded basic and clinical research.
Areas of research expertise in the department include educational and quality assurance research, pain management studies, and experimental therapeutics. In addition, the department has collaborations with numerous colleges and departments on campus, which can provide other opportunities.

Summary of Research Activities

Funded Research

Faculty


Title of Grant


Agency and Acct #


Funding
Period


Napolitano CA (PI)


Incidence of Perioperative Ventricular Tachydysrhythmias In Cardiopulmonary Bypass Patients


Ischemic Research & Education Fnd


Zabala LM (PI)Schmitz ML, Jaquiss RDB, Imamura M, Martin TW, Bhutta A, Hussain S


A Phase II Multicenter, Randomized, Double-Blind, Parallel Group, Dose-Ranging, Effect-Controlled Study to Determine the Pharmacokinetics and Pharmacodynamics of Sodium Nitroprusside in Pediatric Subjects


NICHD-2003-09-DR


11/06 - present


Interdisciplinary Research

Name of Project/Grant


Faculty Involved


Institutions


Length of Project


Serum Natriuretic Peptide Assays in Children with Dilated Cardiomyopathy: Correlation of serum levels to echocardiographic functional parameters and Clinical symptoms.


Dyamenahalli U, Morrow WR, Frazier EA, Apuya J, and Kajevska IH


ACH


Expression and function of Na+,K+-ATPase in rat calx synapse


Dobretsov M, Von Gersdorff, H


UAMS, Oregon Health Sci U


Expression of beta 3 subunit of Na+,K+-ATPase and pain in mice


Dobretsov M, Mogil J, Clark D


UAMS, Pain Genetics Lab, Canada, Stanford


Ketamine Pharmacokinetics in Children Undergoing Cardiac Surger


Bhutta A (PI); Stowe C, Schmitz ML, Zabala L, Ullah S, Jaquiss RDB, Imamura M, James L, Watkins WB


ACH


02/07 - present


Pediatric Mobile Cardiac ECMO: A Single Institution Experience


Cabrera A (PI)  Schmitz ML, Fiser R, Imamura M, Jaquiss RDB, Fiser WP


ACH


04/06 - present


Thromboelastogam Blood Analysis of Pediatric Cardiac Surgery Patients


Schmitz ML (PI) Fiser WP, Zabala LM


ACH


04/07 - present


Internet Use by Parents Regarding Their Child¹s Surgical Procedure at Arkansas Children¹s Hospital



Schmitz ML (PI) Pierce CD; Martin TW, Killebrew PM, Simpson PM, Zabala LM


ACH


02/07 - present


Obesity Incidence in Children with Congenital Heart Disease


Ray T (PI) Jaquiss RDB, Imamura M, Schmitz ML, Best T.


ACH


02/06 - present


Diagnosis of Hemangiomas and Vascular Malformations Using Non-Invasive Imaging Devices


Stack B (PI), Kokoska M, Shafirstein G, Suen J, Buckmiller L, James CJ, Nicholas R, Schmitz ML, Vural EA.


ACH/UAMS


01/06 - present



Entropy and Fractal Pattern of Near Infrared Spectoscopy Measurements in Children with Heart Disease


Bhutta A (PI),Tuzcu V, Nas S, Prodham P, Ullah S, Watkins WB, Zabala LM, Schmitz ML, Imamura M, Jaquiss RDB, Dyamenahalli U


ACH


06/06 - present


Lactate Levels in Children with Atrial Septal Defects Undergoing Surgical Repair


Prodham P (PI); Jaquiss RDB, Bhutta A, Dyamenahalli U, Schmitz ML


ACH


05/06 - present



Ultrasonography of Neonatal Blood Vessels: Implications for Vascular Access


Prodhan P (PI); Dyamenahalli U, Schmitz ML, Zabala L, Lyle R, Ullah S


ACH


02/06- present


Use of Ketamine Prior to Cardiopulmonary Bypass in Children


Bhutta A (PI), Fontenot E, Drummond-Webb JJ, Schmitz ML, Anand KS, Kajevska I, James LG, Simpson PM, Ward-Begnoche W


ACH


04/04 - present


A Three Year Retrospective Review of the Use of Aprotinin to Reduce Blood Loss During Idiopathic Scoliosis Surgery at Arkansas Children’s Hospital


Al-Takrouri H (PI), Martin TW, Siddiqui S, Schmitz ML, McCarthy R, Simpson P


ACH


06/06 - present


A Multicenter, Inpatient, Open-Label, within Subject Dose Titration Study to Characterize the Pharmacokinetics/Pharmacodynamics, Safety and Efficacy of Hydromorphone HCl Oral Solution in Subjects from 28 Days to 16 Years of Age, Inclusive, Who Require Opioid Analgesics for Postoperative Pain


Schmitz ML (PI),Sangari TS, Bhutta A, Zabala LM, Guatam NK, Siddiqui MS, Killebrew PM, Pierce CD


ACH and Purdue Pharma L.P


04/07 - present